Overview

  • Product name

    Anti-Bcl 7A antibody - C-terminal
    See all Bcl 7A primary antibodies
  • Description

    Rabbit polyclonal to Bcl 7A - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant fragment, corresponding to a region within C-terminal amino acids 148-210 of Human Bcl 7A (Uniprot ID: Q4VC05).

  • Positive control

    • Recombinant Human Bcl 7A protein (ab131815) can be used as a positive control in WB. HeLa S3 whole cell lysate; Human oral CA cell line Ca922 xenograft tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab137362 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 23 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Antigen retrieval using heat mediated Tris-EDTA buffer (pH8.0) is also possible.

Target

  • Involvement in disease

    Note=Chromosomal aberrations involving BCL7A may be a cause of B-cell non-Hodgkin lymphoma. Three-way translocation t(8;14;12)(q24.1;q32.3;q24.1) with MYC and with immunoglobulin gene regions.
  • Sequence similarities

    Belongs to the BCL7 family.
  • Post-translational
    modifications

    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt
  • Database links

  • Alternative names

    • B cell CLL/lymphoma 7 antibody
    • B cell CLL/lymphoma 7 protein family member A antibody
    • B cell CLL/lymphoma 7A antibody
    • B-cell CLL/lymphoma 7 protein family member A antibody
    • BCL 7 antibody
    • BCL7 antibody
    • bcl7a antibody
    • BCL7A_HUMAN antibody
    see all

Images

  • Anti-Bcl 7A antibody - C-terminal (ab137362) at 1/1000 dilution + HeLa S3 cell lysate at 30 µg

    Predicted band size: 23 kDa



    15% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Human oral CA cell line Ca922 xenograft labelling Bcl 7A with ab137362 at 1/100 dilution.

References

ab137362 has not yet been referenced specifically in any publications.

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