Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab221627 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 1 - 4 µg/ml.
Fixation/Permeabilization: PFA/Triton X-100.
FunctionTranscriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence specific DNA-binding proteins such as BCL6. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor.
Tissue specificityDetected in testis and prostate. Detected at lower levels in peripheral blood leukocytes and spleen.
Sequence similaritiesBelongs to the BCOR family.
Contains 3 ANK repeats.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
- Information by UniProt
FormThere are 3 isoforms produced by alternative splicing.
- BCL-6 corepressor-like protein 1 antibody
- BCL6 co-repressor-like 1 antibody
- BCL6 corepressor-like 1 antibody
ab221627 has not yet been referenced specifically in any publications.