Key features and details
- Rabbit polyclonal to BCS1L
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-BCS1L antibody
See all BCS1L primary antibodies
DescriptionRabbit polyclonal to BCS1L
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Human
Recombinant full length protein, corresponding to amino acids 1-419 of Human BCS1L (NP_004319.1).
- Mouse spleen tissue lysate; BCS1L transfected 293T cell line lysate
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Constituent: 2.68% PBS
Concentration information loading...
PurityProtein A purified
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
Our Abpromise guarantee covers the use of ab102808 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 48 kDa.|
RelevanceBCS1L (BCS1-like) is a chaperone necessary for the assembly of mitochondrial respiratory chain complex III. The protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Two alternatively spliced transcripts encoding the same protein have been described.
Cellular localizationMitochondrial. Mitochondrion inner membrane. Single-pass membrane protein.
- BCS 1 antibody
- BCS 1L antibody
- BCS antibody
Anti-BCS1L antibody (ab102808) at 5 µg/ml + Mouse spleen tissue lysate at 50 µg
Goat anti-Mouse IgG HRP at 1/2500 dilution
Predicted band size: 48 kDa
All lanes : Anti-BCS1L antibody (ab102808) at 5 µg/ml
Lane 1 : BCS1L transfected 293T cell line lysate
Lane 2 : Non-transfected 293T cell line lysate
Lysates/proteins at 25 µg per lane.
All lanes : Goat anti-Mouse IgG HRP at 1/2500 dilution
Predicted band size: 48 kDa
ab102808 has been referenced in 2 publications.
- Lobo-Jarne T et al. Human COX7A2L Regulates Complex III Biogenesis and Promotes Supercomplex Organization Remodeling without Affecting Mitochondrial Bioenergetics. Cell Rep 25:1786-1799.e4 (2018). PubMed: 30428348
- Chen X et al. Artesunate Activates the Intrinsic Apoptosis of HCT116 Cells through the Suppression of Fatty Acid Synthesis and the NF-?B Pathway. Molecules 22:N/A (2017). PubMed: 28786914