BD 1008 dihydrobromide, delta1-receptor antagonist (ab144559)

Overview

  • Product name

    BD 1008 dihydrobromide, delta1-receptor antagonist
  • Description

    Potent and selective δ1-receptor antagonist
  • Biological description

    Potent and selective δ1-receptor antagonist (Ki = 0.34 nM). Therapeutic agent. Active in vivo and in vitro.
  • Purity

    > 99%
  • CAS Number

    138356-09-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-1-pyrrolidineethanamine dihydrobromide
  • Molecular weight

    463.08
  • Molecular formula

    C15H22Cl2N2.2HBr
  • PubChem identifier

    45073417
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CN(CCC1=CC(=C(C=C1)Cl)Cl)CCN2CCCC2.Br.Br
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Desai RI  et al. Pharmacological characterization of a dopamine transporter ligand that functions as a cocaine antagonist. J Pharmacol Exp Ther 348:106-15 (2014). Read more (PubMed: 24194528) »
  • Hiranita T  et al. Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and s receptors. J Pharmacol Exp Ther 339:662-77 (2011). Read more (PubMed: 21859929) »
  • de Costa BR  et al. Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines: structural requirements and binding affinity at the sigma receptor. J Med Chem 35:38-47 (1992). Read more (PubMed: 1310114) »

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