BD 1047 dihydrobromide, sigma1 receptor antagonist (ab144560)

Overview

  • Product name

    BD 1047 dihydrobromide, sigma1 receptor antagonist
  • Description

    Selective σ1 receptor antagonist
  • Alternative names

    • BD1047 dihydrobromide
  • Biological description

    Selective σ1 receptor antagonist. Shows centrally-mediated antianalgesic, antiaddictive and antidystonic effects in vivo. Blood-brain barrier permeable.

  • Purity

    > 99%
  • CAS Number

    138356-21-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N1-[2-(3,4-Dichlorophenyl)ethyl]-N1,N2,N2-trimethyl-1,2-ethanediamine dihydrobromide
  • Molecular weight

    437.04
  • Molecular formula

    C13H20Cl2N2.2HBr
  • PubChem identifier

    45073418
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM and in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CN(C)CCN(C)CCC1=CC(=C(C=C1)Cl)Cl.Br.Br
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Hiranita T  et al. Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and s receptors. J Pharmacol Exp Ther 339:662-77 (2011). Read more (PubMed: 21859929) »
  • Wu HE  et al. Stereoselective action of (+)-morphine over (-)-morphine in attenuating the (-)-morphine-produced antinociception via the naloxone-sensitive sigma receptor in the mouse. Eur J Pharmacol 571:145-51 (2007). Read more (PubMed: 17617400) »
  • Matsumoto RR  et al. Characterization of two novel sigma receptor ligands: antidystonic effects in rats suggest sigma receptor antagonism. Eur J Pharmacol 280:301-10 (1995). Read more (PubMed: 8566098) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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