Overview

  • Product name

    Beauvericin, Cyclic hexadepsipeptide mycotoxin
  • Description

    Cyclic hexadepsipeptide mycotoxin
  • Biological description

    Cyclic hexadepsipeptide mycotoxin with insecticidal, antimicrobial, antiviral and cytotoxic activities. Cytotoxic in insect (IC50 = 2.5 μM) and mammalian cells (IC50= 4.5 μM).
  • Purity

    > 95%
  • CAS Number

    26048-05-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (3S,6R,9S,12R,15S,18R)-3,9,15-Tribenzyl-4,10,16-trimethyl-6,12,18-tri(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone
  • Molecular weight

    783.95
  • Molecular formula

    C45H57N3O9
  • PubChem identifier

    105014
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 25 mM and in ethanol to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C)C1C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)O1)CC2=CC=CC=C2) C)C(C)C)CC3=CC=CC=C3)C)C(C)C)CC4=CC=CC=C4)C
  • Source

    Beauveria bassiana

  • Research areas

References

This product has been referenced in:

  • Wang Q & Xu L Beauvericin, a bioactive compound produced by fungi: a short review. Molecules 17:2367-77 (2012). Read more (PubMed: 22367030) »
  • Tonshin AA  et al. The Fusarium mycotoxins enniatins and beauvericin cause mitochondrial dysfunction by affecting the mitochondrial volume regulation, oxidative phosphorylation and ion homeostasis. Toxicology 276:49-57 (2010). Read more (PubMed: 20621153) »
  • Santini A  et al. Overview of analytical methods for beauvericin and fusaproliferin in food matrices. Anal Bioanal Chem 395:1253-60 (2009). Read more (PubMed: 19774368) »

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