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Rabbit polyclonal to Beclin 1 (phospho S295)
ab183313 only detects Beclin 1 when phosphorylated at serine 295. Immunolabeling of the Beclin 1 band is eliminated in the Beclin 1 alanine substitution mutant. Additional bands may be observed in non-immunoprecipitated lysates.
Predicted to work with:
Mouse, Sheep, Chicken, Cow, Dog, Xenopus laevis, Non human primates, Zebrafish
Synthetic peptide corresponding to Human Beclin 1 (phospho S295).
Database link: Q14457
DDDDK Beclin 1 WT immunoprecipitates expressed in 293T cells.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Constituents: 0.24% HEPES, 0.88% Sodium chloride, 50% Glycerol, 0.01% BSA
Concentration information loading...
Immunogen affinity purified
ab183313 was prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/250. Predicted molecular weight: 52 kDa.
Plays a central role in autophagy (By similarity). May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.
Belongs to the beclin family.
Golgi apparatus > trans-Golgi network membrane. Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells.
Information by UniProt
ATG 6 antibody
has not yet been referenced specifically in any publications.
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