Benazepril hydrochloride, Angiotensin-converting enzyme (ACE) inhibitor (ab141166)
Key features and details
- Angiotensin-converting enzyme (ACE) inhibitor. Prodrug.
- CAS Number: 86541-74-4
- Purity: > 99%
- Soluble in water to 25 mM, in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Benazepril hydrochloride, Angiotensin-converting enzyme (ACE) inhibitor -
Description
Angiotensin-converting enzyme (ACE) inhibitor. Prodrug. -
Biological description
Angiotensin-converting enzyme (ACE) inhibitor (IC50 = 0.27 nM). Prodrug. Orally active in vivo. Antihypertensive. Minimal ability to cross the blood-brain barrier.
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Purity
> 99% -
CAS Number
86541-74-4 -
Chemical structure
Properties
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Chemical name
3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid hydrochloride -
Molecular weight
460.96 -
Molecular formula
C24H28N2O5.HCl -
PubChem identifier
5362123 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 25 mM, in ethanol to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.O=C(OCC)C(CCc1ccccc1)NC3CCc2ccccc2N(CC(=O)O)C3=O -
Source
Synthetic
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Research areas
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Retinoic & Retinoid
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Orphan Nuclear Receptors
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Molecular processes
- Mitochondrial transcription
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab141166 has not yet been referenced specifically in any publications.