Key features and details
- Mutagenic agent
- CAS Number: 50-32-8
- Purity: > 98%
- Form / State: Solid
- Source: Synthetic
Product nameBenzo[a]pyrene (B[a]P), Mutagenic agent
Biological descriptionMutagenic agent. Inhibits EROD activtiy (IC50 values are 31, 140 and 350 nM at P450 1B1, 1A2 and 1A1 respectively). Causes DNA adducts in vivo. Upregulates the expression of HPV E7oncoprotein. Orally active.
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Epigenetics and Nuclear Signaling
- Domain Families
- HLH / Leucine Zipper
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142566 has not yet been referenced specifically in any publications.