Key features and details
- Cell-permeable derivative of Bestatin (ab141417); neutral aminopeptidase inhibitor.
- CAS Number: 65322-89-6
- Purity: > 97%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Product nameBestatin methyl ester, neutral aminopeptidase inhibitor
DescriptionCell-permeable derivative of Bestatin (ab141417); neutral aminopeptidase inhibitor.
- (-)-N-[(2S, 3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine Methyl Ester
- Methyl Bestatin
Cell-permeable derivative of Bestatin (ab141417). Displays slightly stronger inhibition of neutral aminopeptidase than Bestatin but has much weaker activity against basic aminopeptidase. Augments Fas- or TNF-α-induced apoptosis in solid tumor cell lines.
Chemical name(-)-N-[(2S, 3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine methyl ester
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab145909 has not yet been referenced specifically in any publications.