Key features and details
- Chicken polyclonal to beta 3 Adrenergic Receptor
- Reacts with: Mouse, Rat
- Isotype: IgY
Product nameAnti-beta 3 Adrenergic Receptor antibody
See all beta 3 Adrenergic Receptor primary antibodies
DescriptionChicken polyclonal to beta 3 Adrenergic Receptor
Species reactivityReacts with: Mouse, Rat
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Cholesterol Metabolism
FunctionBeta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
Tissue specificityExpressed mainly in adipose tissues.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.
Cellular localizationCell membrane.
- Information by UniProt
- ADR B3 antibody
- ADRB 3 antibody
- ADRB3 antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab59685 has been referenced in 8 publications.
- Lee HH et al. TonEBP/NFAT5 promotes obesity and insulin resistance by epigenetic suppression of white adipose tissue beiging. Nat Commun 10:3536 (2019). PubMed: 31387996
- Löffler MC et al. Protein kinase D1 deletion in adipocytes enhances energy dissipation and protects against adiposity. EMBO J 37:N/A (2018). PubMed: 30389661
- Saxton SN et al. Role of Sympathetic Nerves and Adipocyte Catecholamine Uptake in the Vasorelaxant Function of Perivascular Adipose Tissue. Arterioscler Thromb Vasc Biol 38:880-891 (2018). PubMed: 29496660
- Choo MS et al. The preventive effect of a free radical scavenger on oxidative stress after the relief of partial bladder outlet obstruction in a rat model. PLoS One 13:e0199800 (2018). PubMed: 30346942
- Winder M et al. Autonomic Receptor-mediated Regulation of Production and Release of Nitric Oxide in Normal and Malignant Human Urothelial Cells. Basic Clin Pharmacol Toxicol 121:257-265 (2017). PubMed: 28437032
- Oue K et al. Phospholipase C-related Catalytically Inactive Protein Is a New Modulator of Thermogenesis Promoted by ß-Adrenergic Receptors in Brown Adipocytes. J Biol Chem 291:4185-96 (2016). WB ; Mouse . PubMed: 26706316
- Okumura T et al. Phospholipase C-Related Catalytically Inactive Protein (PRIP) Regulates Lipolysis in Adipose Tissue by Modulating the Phosphorylation of Hormone-Sensitive Lipase. PLoS One 9:e100559 (2014). WB ; Mouse . PubMed: 24945349
- Salisbury EA et al. Transient brown adipocyte-like cells derive from peripheral nerve progenitors in response to bone morphogenetic protein 2. Stem Cells Transl Med 1:874-85 (2012). Flow Cyt ; Mouse . PubMed: 23283549