Product nameAnti-beta 3 Adrenergic Receptor antibody
See all beta 3 Adrenergic Receptor primary antibodies
DescriptionRabbit polyclonal to beta 3 Adrenergic Receptor
Tested applicationsSuitable for: WB, ELISAmore details
Species reactivityReacts with: Human
A synthetic peptide derived from an internal region of human beta 3 Adrenergic Receptor.
- Extracts from K562 cells
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Concentration information loading...
PurityImmunogen affinity purified
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Cholesterol Metabolism
Our Abpromise guarantee covers the use of ab76249 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 44 kDa.|
FunctionBeta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
Tissue specificityExpressed mainly in adipose tissues.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.
Cellular localizationCell membrane.
- Information by UniProt
- ADR B3 antibody
- ADRB 3 antibody
- ADRB3 antibody
All lanes : Anti-beta 3 Adrenergic Receptor antibody (ab76249) at 1/500 dilution
Lane 1 : Extracts from K562 cells
Lane 2 : Extracts from K562 cells with immunising peptide at 5 µg
Lysates/proteins at 5 µg per lane.
Predicted band size: 44 kDa
Observed band size: 35 kDa why is the actual band size different from the predicted?
This product has been referenced in:
- Deng J et al. Targeting ß3-adrenergic receptor signaling inhibits neuroblastoma cell growth via suppressing the mTOR pathway. Biochem Biophys Res Commun 514:295-300 (2019). Read more (PubMed: 31030945) »
- Chisholm KM et al. ß-Adrenergic receptor expression in vascular tumors. Mod Pathol 25:1446-51 (2012). IHC-P ; Human . Read more (PubMed: 22743651) »