Overview

  • Product name

    Anti-beta 3 Adrenergic Receptor antibody
    See all beta 3 Adrenergic Receptor primary antibodies
  • Description

    Goat polyclonal to beta 3 Adrenergic Receptor
  • Host species

    Goat
  • Tested applications

    Suitable for: WB, ELISAmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Chimpanzee
  • Immunogen

    Synthetic peptide:

    PHENSSLAPWPD-C

    , corresponding to N terminal amino acids 5-16 of human beta 3 Adrenergic Receptor (NP_000016.1)

  • Positive control

    • Human brain (cerebellum, cerebral cortex, frontal cortex) lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab77588 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    Peptide ELISA: Antibody detection limit dilution 1/128000.
    WB: Use at a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
    • Tissue specificity

      Expressed mainly in adipose tissues.
    • Sequence similarities

      Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.
    • Cellular localization

      Cell membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • ADR B3 antibody
      • ADRB 3 antibody
      • ADRB3 antibody
      • ADRB3_HUMAN antibody
      • ADRB3R antibody
      • Adrenergic beta 3 receptor antibody
      • B3AR antibody
      • Beta 3 adrenoceptor antibody
      • Beta 3 adrenoreceptor antibody
      • Beta 3AR antibody
      • Beta-3 adrenergic receptor antibody
      • Beta-3 adrenoceptor antibody
      • Beta-3 adrenoreceptor antibody
      • Beta3AR antibody
      • FLJ99960 antibody
      see all

    Images

    • Anti-beta 3 Adrenergic Receptor antibody (ab77588) at 0.03 µg/ml + human brain (cerebral cortex) lysate (in RIPA buffer) at 35 µg

      Predicted band size: 45 kDa
      Observed band size: 45 kDa



      Primary incubation was 1 hour.

    References

    This product has been referenced in:

    • Pasha A  et al. ß3-Adrenoreceptor Activity Limits Apigenin Efficacy in Ewing Sarcoma Cells: A Dual Approach to Prevent Cell Survival. Int J Mol Sci 20:N/A (2019). Read more (PubMed: 31052299) »
    • O'Leary AP  et al. Beta-Adrenoceptor Activation Reduces Both Dermal Microvascular Endothelial Cell Migration Via a cAMP-Dependent Mechanism and Wound Angiogenesis. J Cell Physiol N/A:N/A (2014). WB ; Human . Read more (PubMed: 24986762) »
    See all 2 Publications for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab77588.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    Sign up