Overview

  • Product name

    Anti-beta 3 Adrenergic Receptor antibody - C-terminal
    See all beta 3 Adrenergic Receptor primary antibodies
  • Description

    Rabbit polyclonal to beta 3 Adrenergic Receptor - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Monkey, Gorilla
  • Immunogen

    Synthetic peptide, corresponding to an 18 residue sequence within C terminal amino acids of Human beta 3 Adrenergic Receptor (NP_000016.1).

  • Positive control

    • Human adipose tissue

Applications

Our Abpromise guarantee covers the use of ab140709 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 36 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
  • Tissue specificity

    Expressed mainly in adipose tissues.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • ADR B3 antibody
    • ADRB 3 antibody
    • ADRB3 antibody
    • ADRB3_HUMAN antibody
    • ADRB3R antibody
    • Adrenergic beta 3 receptor antibody
    • B3AR antibody
    • Beta 3 adrenoceptor antibody
    • Beta 3 adrenoreceptor antibody
    • Beta 3AR antibody
    • Beta-3 adrenergic receptor antibody
    • Beta-3 adrenoceptor antibody
    • Beta-3 adrenoreceptor antibody
    • Beta3AR antibody
    • FLJ99960 antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed, paraffin embedded Human adipose tissue labelling beta 3 Adrenergic Receptor with ab140709 at 36 µg/ml.

References

ab140709 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Answer

Neither of the beta 3 Adrenergic Receptor antibodies you asked about have been tested for ICC/IF, only IHC. If you do decide to try one, you will be better off with ab140709. The immunogen shares only 22% identity with the mouse protein, and the immunogen for ab140713 shares 75% identity. Reactivity with mouse has not, however, been tested by experiment.

Read More

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