Product nameAnti-beta 3 Adrenergic Receptor antibody - N-terminal
See all beta 3 Adrenergic Receptor primary antibodies
DescriptionRabbit polyclonal to beta 3 Adrenergic Receptor - N-terminal
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Rabbit, Guinea pig, Monkey, Gorilla, Elephant
Synthetic peptide, corresponding to a 20 residue sequence within N terminal (extracellular domain) amino acids of Human beta 3 Adrenergic Receptor (NP_000016.1).
- Human adipose tissue
Storage instructionsShipped at 4°C.
Storage bufferPreservative: 0.1% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Cholesterol Metabolism
Our Abpromise guarantee covers the use of ab140713 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 17 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionBeta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
Tissue specificityExpressed mainly in adipose tissues.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.
Cellular localizationCell membrane.
- Information by UniProt
- ADR B3 antibody
- ADRB 3 antibody
- ADRB3 antibody
ab140713 has been referenced in 1 publication.
- Deng J et al. Targeting ß3-adrenergic receptor signaling inhibits neuroblastoma cell growth via suppressing the mTOR pathway. Biochem Biophys Res Commun 514:295-300 (2019). PubMed: 31030945