Overview

  • Product name
    beta-Amyloid Peptide (1-42) (human)
  • Description
    beta-Amyloid (1-42) protein fragment. Implicated in Alzheimer's disease.
  • Alternative names
    • AB42
  • Biological description

    42-Residue amyloid beta-protein fragment; the predominant form of amyloid beta found in the brains of people with Alzheimer's disease and Down's syndrome. Neurotoxic. Shown to induce neuronal death via actions at the p75 neurotrophin receptor.

  • Purity
    > 95%

Properties

Protocols

References

This product has been referenced in:
  • Sotthibundhu A  et al. Beta-amyloid(1-42) induces neuronal death through the p75 neurotrophin receptor. J Neurosci 28:3941-6 (2008). Read more (PubMed: 18400893) »
  • Nagele RG  et al. Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in Alzheimer's disease. Neuroscience 110:199-211 (2002). Read more (PubMed: 11958863) »
  • Roher AE  et al. beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease. Proc Natl Acad Sci U S A 90:10836-40 (1993). Read more (PubMed: 8248178) »
See all 6 Publications for this product

Customer reviews and Q&As

1-4 of 4 Abreviews or Q&A

ab120301 worked very well as a comparison in our dot blot experiment attempting to locate amyloid beta in the nasal mucous of humans. As seen in the depiction it clearly appeared as expected after dilution and when using it to spike certain samples. The product manual and data sheet were both accurate and very easy to follow and allowed us to more easily conduct the experiment.

Abcam user community

Verified customer

Submitted Mar 20 2019

Answer

Thank you for your reply.

I am sending you a quotation for 5 x 1mg of ab120301. All you will need to place the order is to confirm your shipping address, billing address, phone number, and PO number.

If in the future you are interested in ordering more than 10 vials, please contact my colleagues at sales@abcam.com and they will be happy to helpyou to arrange a bulk discount. Please let me know if you need any additional information or assistance.

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Answer

Thank you for your reply. Unfortunately, we are unable to provide additional Mass Spec data for this product. We will cover it under our 100% Abpromise guarantee. If for any reason you are not satisfied with the quality, we will be happy to refund or replace it if you let us know within six months of purchase.


I hope this helps, please let me know if you have any additional questions or concerns.

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Question
Answer

Thank you for contacting us.

Please find the requested Mass Spec graph attached. I hope this helps, please let me know if you need any additional information.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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