Anti-BD-3 antibody (ab19270)
Key features and details
- Rabbit polyclonal to BD-3
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-BD-3 antibody
See all BD-3 primary antibodies -
Description
Rabbit polyclonal to BD-3 -
Host species
Rabbit -
Tested applications
Suitable for: WB, ICC/IFmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein corresponding to Human BD-3.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
-
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab19270 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
Use at an assay dependent concentration.
|
|
ICC/IF |
Use at an assay dependent concentration. PubMed: 23627872
|
Notes |
---|
WB
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. PubMed: 23627872 |
Target
-
Function
Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed. -
Tissue specificity
Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. -
Sequence similarities
Belongs to the beta-defensin family. -
Cellular localization
Secreted. - Information by UniProt
-
Database links
- Entrez Gene: 414325 Human
- Entrez Gene: 55894 Human
- SwissProt: P81534 Human
- Unigene: 283082 Human
- Unigene: 637221 Human
-
Alternative names
- BD 3 antibody
- BD-3 antibody
- BD3 antibody
see all
Protocols
Datasheets and documents
-
SDS download
-
Datasheet download
References (11)
ab19270 has been referenced in 11 publications.
- Sun J et al. Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy. Aging Cell 21:e13532 (2022). PubMed: 34905649
- Šerstņova K et al. Expression of anti-inflammatory markers IL-2, IL-10, TGF-β1, βDEF-2, βDEF-3 and Cathelicidin LL37 in dairy cattle milk with different health status of the udder. Pol J Vet Sci 25:237-248 (2022). PubMed: 35861957
- Li L et al. Gold Nanoparticles Combined Human ß-Defensin 3 Gene-Modified Human Periodontal Ligament Cells Alleviate Periodontal Destruction via the p38 MAPK Pathway. Front Bioeng Biotechnol 9:631191 (2021). PubMed: 33585435
- Boer DEC et al. Skin of atopic dermatitis patients shows disturbed ß-glucocerebrosidase and acid sphingomyelinase activity that relates to changes in stratum corneum lipid composition. Biochim Biophys Acta Mol Cell Biol Lipids 1865:158673 (2020). PubMed: 32092464
- Li L et al. Human ß-defensin 3 gene modification promotes the osteogenic differentiation of human periodontal ligament cells and bone repair in periodontitis. Int J Oral Sci 12:13 (2020). PubMed: 32350241