beta-Amyloid Peptide (1-42) (rat/mouse) (ab120959)
Key features and details
- Rat form of the beta-Amyloid (1-42) peptide
- CAS Number: 166090-74-0
- Soluble in 1%NH4OH/Water to 1mg/ml
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
beta-Amyloid Peptide (1-42) (rat/mouse) -
Description
Rat form of the beta-Amyloid (1-42) peptide -
CAS Number
166090-74-0 -
Chemical structure
Properties
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Molecular weight
4417.99 -
Molecular formula
C199H307N53O59S -
Sequence
DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIA -
PubChem identifier
71581490 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in 1%NH4OH/Water to 1mg/ml -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (8)
ab120959 has been referenced in 8 publications.
- Kang BW et al. Phosphodiesterase 5 inhibitor mirodenafil ameliorates Alzheimer-like pathology and symptoms by multimodal actions. Alzheimers Res Ther 14:92 (2022). PubMed: 35804462
- Bahlakeh G et al. Neurotrophic factor-secreting cells restored endogenous hippocampal neurogenesis through the Wnt/β-catenin signaling pathway in AD model mice. Stem Cell Res Ther 13:343 (2022). PubMed: 35883119
- Hadipour M et al. Administering crocin ameliorates anxiety-like behaviours and reduces the inflammatory response in amyloid-beta induced neurotoxicity in rat. Clin Exp Pharmacol Physiol 48:877-889 (2021). PubMed: 33686675
- Mokarizadeh N et al. ß-Lapachone attenuates cognitive impairment and neuroinflammation in beta-amyloid induced mouse model of Alzheimer's disease. Int Immunopharmacol 81:106300 (2020). PubMed: 32070922
- Rao CV et al. GSK3-ARC/Arg3.1 and GSK3-Wnt signaling axes trigger amyloid-ß accumulation and neuroinflammation in middle-aged Shugoshin 1 mice. Aging Cell 19:e13221 (2020). PubMed: 32857910
- Illouz T et al. Restoring microglial and astroglial homeostasis using DNA immunization in a Down Syndrome mouse model. Brain Behav Immun 75:163-180 (2019). PubMed: 30389461
- Rahman MA et al. Brain proteomics links oxidative stress with metabolic and cellular stress response proteins in behavioural alteration of Alzheimer's disease model rats. AIMS Neurosci 6:299-315 (2019). PubMed: 32341985
- Nguyen TV et al. Alzheimer's associated amyloid and tau deposition co-localizes with a homeostatic myelin repair pathway in two mouse models of post-stroke mixed dementia. Acta Neuropathol Commun 6:100 (2018). PubMed: 30249297