Overview

  • Product name

    beta-Amyloid Peptide (12-28)
  • Description

    Toxic beta-Amyloid peptide (12-28) fragment
  • Biological description

    Amyloid beta peptide fragment. Aggregates and displays toxic effect in vitro. Also shows amnestic effect in vivo following i.c.v administration. Additionally binds α7-nicotinic ACh receptors with high affinity.

  • CAS Number

    107015-83-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Cao Z  et al. Effects of different force fields and temperatures on the structural character of abeta (12-28) Peptide in aqueous solution. Int J Mol Sci 12:8259-74 (2011). Read more (PubMed: 22174662) »
  • Flood JF  et al. An amyloid beta-protein fragment, A beta[12-28], equipotently impairs post-training memory processing when injected into different limbic system structures. Brain Res 663:271-6 (1994). Read more (PubMed: 7874511) »
  • Flood JF  et al. Amnestic effects in mice of four synthetic peptides homologous to amyloid beta protein from patients with Alzheimer disease. Proc Natl Acad Sci U S A 88:3363-6 (1991). Read more (PubMed: 2014256) »

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