Overview

  • Product name

    beta-Carotene, Antioxidant
  • Description

    Antioxidant known to inhibit carcinogenisis
  • Biological description

    Carotenoid precursor of vitamin A. High-affinity antagonist for RARα, RARβ, and RARγ. Modulates intracellular redox status affecting redox-sensitive pathways involved in the regulation of cell cycle progression and apoptosis. Active in vivo and in vitro.
  • Purity

    > 97%
  • CAS Number

    7235-40-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1,3,3-Trimethyl-2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohexene
  • Molecular weight

    536.87
  • Molecular formula

    C40H56
  • PubChem identifier

    5280489
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(CCCC2(C)C)C)C)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Harrison EH  et al. The formation, occurrence, and function of ß-apocarotenoids: ß-carotene metabolites that may modulate nuclear receptor signaling. Am J Clin Nutr 96:1189S-92S (2012). Read more (PubMed: 23053561) »
  • Palozza P Can beta-carotene regulate cell growth by a redox mechanism? An answer from cultured cells. Biochim Biophys Acta 1740:215-21 (2005). Read more (PubMed: 15949689) »
  • Sommerburg O  et al. Proteasomal degradation of beta-carotene metabolite--modified proteins. Biofactors 35:449-59 (0). Read more (PubMed: 19787777) »

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