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    beta-defensin-1-antibody-ab115813.pdf

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Microbiology Protein Human Protein Defensin
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Anti-beta Defensin 1 antibody (ab115813)

  • Datasheet
  • SDS
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Western blot - Anti-beta Defensin 1 antibody (ab115813)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-beta Defensin 1 antibody (ab115813)

Key features and details

  • Rabbit polyclonal to beta Defensin 1
  • Suitable for: WB, IHC-P
  • Reacts with: Human
  • Isotype: IgG

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Secondary
Product image
Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
Protein
Recombinant human beta Defensin 1 protein (ab50048)

View more associated products

Overview

  • Product name

    Anti-beta Defensin 1 antibody
    See all beta Defensin 1 primary antibodies
  • Description

    Rabbit polyclonal to beta Defensin 1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a sequence at the C terminal of Human beta Defensin 1.

  • Positive control

    • IHC: Human lung cancer tissue. WB: COLO320 Whole Cell Lysate.
  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
    Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Microbiology
    • Protein
    • Human Protein
    • Defensin

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Recombinant Protein

    • Recombinant human beta Defensin 1 protein (ab50048)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab115813 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
Use a concentration of 0.5 µg/ml. Predicted molecular weight: 7 kDa.
IHC-P
Use a concentration of 1 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Notes
WB
Use a concentration of 0.5 µg/ml. Predicted molecular weight: 7 kDa.
IHC-P
Use a concentration of 1 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Has bactericidal activity.
  • Tissue specificity

    Plasma.
  • Sequence similarities

    Belongs to the beta-defensin family.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession P60022 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 1672 Human
    • Omim: 602056 Human
    • SwissProt: P60022 Human
    • Unigene: 32949 Human
    • Alternative names

      • BD 1 antibody
      • BD-1 antibody
      • BD1 antibody
      • beta 1 antibody
      • Beta defensin 1 antibody
      • Beta-defensin 1 antibody
      • DEFB 1 antibody
      • DEFB1 antibody
      • DEFB1_HUMAN antibody
      • DEFB101 antibody
      • Defensin antibody
      • Defensin beta 1 antibody
      • Defensin beta 1 preproprotein antibody
      • HBD 1 antibody
      • hBD-1 antibody
      • HBD1 antibody
      • MGC51822 antibody
      see all

    Images

    • Western blot - Anti-beta Defensin 1 antibody (ab115813)
      Western blot - Anti-beta Defensin 1 antibody (ab115813)
      Anti-beta Defensin 1 antibody (ab115813) at 0.5 µg/ml + COLO320 Whole Cell Lysate at 40 µg

      Predicted band size: 7 kDa

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-beta Defensin 1 antibody (ab115813)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-beta Defensin 1 antibody (ab115813)
      ab115813 at 1µg/ml staining beta Defensin 1 in by Paraffin-embedded Human Lung cancer tissue by Immunohistochemistry,

    Protocols

    • Immunohistochemistry protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (2)

    Publishing research using ab115813? Please let us know so that we can cite the reference in this datasheet.

    ab115813 has been referenced in 2 publications.

    • Van Cleemput J  et al. An Alphaherpesvirus Exploits Antimicrobial ß-Defensins To Initiate Respiratory Tract Infection. J Virol 94:N/A (2020). PubMed: 31996426
    • Lee M  et al. Targeting PI3K/mTOR Signaling Displays Potent Antitumor Efficacy against Nonfunctioning Pituitary Adenomas. Clin Cancer Res 21:3204-15 (2015). PubMed: 25838390

    Customer reviews and Q&As

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