Anti-beta Defensin 1 antibody (ab115813)
Key features and details
- Rabbit polyclonal to beta Defensin 1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-beta Defensin 1 antibody
See all beta Defensin 1 primary antibodies -
Description
Rabbit polyclonal to beta Defensin 1 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to a sequence at the C terminal of Human beta Defensin 1.
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Positive control
- IHC: Human lung cancer tissue. WB: COLO320 Whole Cell Lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab115813 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
Use a concentration of 0.5 µg/ml. Predicted molecular weight: 7 kDa.
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| IHC-P |
Use a concentration of 1 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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| Notes |
|---|
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WB
Use a concentration of 0.5 µg/ml. Predicted molecular weight: 7 kDa. |
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IHC-P
Use a concentration of 1 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Has bactericidal activity. -
Tissue specificity
Plasma. -
Sequence similarities
Belongs to the beta-defensin family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 1672 Human
- Omim: 602056 Human
- SwissProt: P60022 Human
- Unigene: 32949 Human
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Alternative names
- BD 1 antibody
- BD-1 antibody
- BD1 antibody
see all
Images
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Western blot - Anti-beta Defensin 1 antibody (ab115813)Anti-beta Defensin 1 antibody (ab115813) at 0.5 µg/ml + COLO320 Whole Cell Lysate at 40 µg
Predicted band size: 7 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-beta Defensin 1 antibody (ab115813)ab115813 at 1µg/ml staining beta Defensin 1 in by Paraffin-embedded Human Lung cancer tissue by Immunohistochemistry,
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab115813 has been referenced in 2 publications.
- Van Cleemput J et al. An Alphaherpesvirus Exploits Antimicrobial ß-Defensins To Initiate Respiratory Tract Infection. J Virol 94:N/A (2020). PubMed: 31996426
- Lee M et al. Targeting PI3K/mTOR Signaling Displays Potent Antitumor Efficacy against Nonfunctioning Pituitary Adenomas. Clin Cancer Res 21:3204-15 (2015). PubMed: 25838390