Anti-beta Endorphin antibody (ab10339)
Key features and details
- Rabbit polyclonal to beta Endorphin
- Suitable for: IHC-P
- Reacts with: Rat
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-beta Endorphin antibody
See all beta Endorphin primary antibodies -
Description
Rabbit polyclonal to beta Endorphin -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Rat -
Immunogen
Antiserum to beta Endorphin was raised in rabbits by using the N-terminal portion of bovine beta Endorphin conjugated to thyroglobulin.
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Positive control
- IHC-P: rat ventral periaqueductal grey matter
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.1% Sodium azide -
Concentration information loading... -
Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab10339 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
Use a concentration of 10 µg/ml.
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| Notes |
|---|
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IHC-P
Use a concentration of 10 µg/ml. |
Target
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Relevance
Beta-endorphin is an endogenous opioid peptide neurotransmitter found in the neurons of both the central and peripheral nervous system. ß-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor pro-opiomelanocortin (POMC). ß-endorphin is found in neurons of the hypothalamus as well as the pituitary gland. It is an agonist of the opioid receptors, with evidence suggesting that it serves as the endogenous ligand of the µ-opioid receptor, the same receptor to which the chemicals extracted from opium, such as morphine and codeine, have their analgesic and addictive effects -
Cellular localization
Secreted -
Database links
- Entrez Gene: 24664 Rat
- SwissProt: P01194 Rat
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Alternative names
- Beta endorphin antibody
- Corticotropin lipotropin antibody
- POMC antibody
- Proopiomelanocortin antibody
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-beta Endorphin antibody (ab10339)
Immunohistochemical analysis of 4% formaldehyde fixed rat ventral periaqueductal grey matter (PAG) labeling beta Endorphin with ab10339 at 10 μg/mL. Donkey anti-rabbit Rhodamine Red conjugated was used as a secondary at 1/200 dilution. Tissue was counterstained with DAPI (blue color) to visualize cell nuclei.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab10339 has been referenced in 1 publication.
- Shi MM et al. Hippocampal µ-opioid receptors on GABAergic neurons mediate stress-induced impairment of memory retrieval. Mol Psychiatry 25:977-992 (2020). PubMed: 31142818