Anti-beta Endorphin antibody (ab10339)

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Key features and details

  • Rabbit polyclonal to beta Endorphin
  • Reacts with: Mouse, Rat, Human
  • Isotype: IgG

Overview

  • Product name

    Anti-beta Endorphin antibody
    See all beta Endorphin primary antibodies

  • Description

    Rabbit polyclonal to beta Endorphin

  • Host species

    Rabbit

  • Species reactivity

    Reacts with: Mouse, Rat, Human

  • Immunogen

    Antiserum to beta Endorphin was raised in rabbits by using the N-terminal portion of bovine beta Endorphin conjugated to thyroglobulin.

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.

    One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.

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Properties

Target

  • Relevance

    Beta-endorphin is an endogenous opioid peptide neurotransmitter found in the neurons of both the central and peripheral nervous system. ß-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor pro-opiomelanocortin (POMC). ß-endorphin is found in neurons of the hypothalamus as well as the pituitary gland. It is an agonist of the opioid receptors, with evidence suggesting that it serves as the endogenous ligand of the µ-opioid receptor, the same receptor to which the chemicals extracted from opium, such as morphine and codeine, have their analgesic and addictive effects

  • Cellular localization

    Secreted

  • Database links

    • Alternative names

      • Beta endorphin antibody
      • Corticotropin lipotropin antibody
      • POMC antibody
      • Proopiomelanocortin antibody

    References (1)

    Publishing research using ab10339? Please let us know so that we can cite the reference in this datasheet.

    ab10339 has been referenced in 1 publication.

    • Shi MM  et al. Hippocampal µ-opioid receptors on GABAergic neurons mediate stress-induced impairment of memory retrieval. Mol Psychiatry 25:977-992 (2020). PubMed: 31142818

    Customer reviews and Q&As

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    Question

    I am interested in two antibodies. Beta endorphin antibody (ab10339) and Beta endorphin antibody (ab8907). Before I purchase one of these, I would like to know what is the immunogen for each one. On the website, it is not specific enough. Thank you for your help.

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    Answer

    Thank you for your patience. Regarding ab10339, antiserum to beta-endorphin was raised in rabbits by using synthetic human beta-endorphin (H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu-OH) conjugated to thyroglobulin. Once I hear back regarding ab8907, I will contact you again.

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