Key features and details
- Coenzyme and enzyme substrate. P2Y11 agonist.
- CAS Number: 53-84-9
- Soluble in water to 50 mM
- Form / State: Solid
- Source: Synthetic
Product namebeta-Nicotinamide adenine dinucleotide (beta-NAD), P2Y11 agonist.
DescriptionCoenzyme and enzyme substrate. P2Y11 agonist.
Major electron acceptor molecule in biological oxidations. Acts as a coenzyme for hydride-transfer enzymes and a substrate for NAD(+)-consuming enzymes, which include ADP-ribose transferases, poly(ADP-ribose) polymerases, cADP-ribose synthases and sirtuins. Recently reported to be a P2Y11 agonist.
Chemical nameDiphosphoric acid-1-adenosin-5'-yl ester-2-[(1S)-1-(3-carbamoylpyridinio)-D-1,4-anhydroribitol-5-yl ester]betaine
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 50 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120403 has been referenced in 1 publication.
- Echeverri Tirado LC et al. PARP-1 Is Critical for Recruitment of Dendritic Cells to the Lung in a Mouse Model of Asthma but Dispensable for Their Differentiation and Function. Mediators Inflamm 2019:1656484 (2019). PubMed: 31178661