Overview

  • Product name

    Anti-beta Sarcoglycan antibody
    See all beta Sarcoglycan primary antibodies
  • Description

    Rabbit polyclonal to beta Sarcoglycan
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide derived from internal sequence of Human beta Sarcoglycan.

  • Positive control

    • A549 cell extract; Human brain tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab135954 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 35 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
  • Tissue specificity

    Highest expression in heart and skeletal muscle. Low expression in brain, kidney, placenta, pancreas and lung. High expression in fetal brain. Also found in fetal lung, kidney and liver.
  • Involvement in disease

    Limb-girdle muscular dystrophy 2E
  • Sequence similarities

    Belongs to the sarcoglycan beta/delta/gamma/zeta family.
  • Post-translational
    modifications

    Disulfide bonds are present.
  • Cellular localization

    Cell membrane, sarcolemma. Cytoplasm, cytoskeleton.
  • Information by UniProt
  • Database links

  • Alternative names

    • 43 kDa dystrophin associated glycoprotein antibody
    • 43 kDa dystrophin-associated glycoprotein antibody
    • 43DAG antibody
    • A3b antibody
    • Beta SG antibody
    • Beta-sarcoglycan antibody
    • Beta-SG antibody
    • dystrophin-associated glycoprotein, 43-kD antibody
    • LGMD2E antibody
    • Limb girdle muscular dystrophy 2E (non linked families) antibody
    • Sarcoglycan beta antibody
    • sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) antibody
    • SGC antibody
    • SGCB antibody
    • SGCB_HUMAN antibody
    see all

Images

  • Anti-beta Sarcoglycan antibody (ab135954) at 1/500 dilution + A549 cell extract at 30 µg

    Predicted band size: 35 kDa

  • Immunohistochemical analysis of paraffin-embedded Human brain tissue labelling beta Sarcoglycan with ab135954 at 1/50 dilution.

References

ab135954 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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