Anti-beta Sarcoglycan antibody (ab203392)
Key features and details
- Rabbit polyclonal to beta Sarcoglycan
- Suitable for: IHC-P
- Reacts with: Mouse, Rat
- Isotype: IgG
Overview
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Product name
Anti-beta Sarcoglycan antibody
See all beta Sarcoglycan primary antibodies -
Description
Rabbit polyclonal to beta Sarcoglycan -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Rat
Predicted to work with: Human
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Immunogen
Synthetic peptide within Human beta Sarcoglycan aa 150-250 conjugated to keyhole limpet haemocyanin. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: Q16585 -
Positive control
- Mouse stomach and rat pancreas tissues.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 1% BSA -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab203392 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
1/100 - 1/500.
|
| Notes |
|---|
|
IHC-P
1/100 - 1/500. |
Target
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Function
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. -
Tissue specificity
Highest expression in heart and skeletal muscle. Low expression in brain, kidney, placenta, pancreas and lung. High expression in fetal brain. Also found in fetal lung, kidney and liver. -
Involvement in disease
Limb-girdle muscular dystrophy 2E -
Sequence similarities
Belongs to the sarcoglycan beta/delta/gamma/zeta family. -
Post-translational
modificationsDisulfide bonds are present. -
Cellular localization
Cell membrane, sarcolemma. Cytoplasm, cytoskeleton. - Information by UniProt
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Database links
- Entrez Gene: 6443 Human
- Entrez Gene: 24051 Mouse
- Entrez Gene: 680229 Rat
- Omim: 600900 Human
- SwissProt: Q16585 Human
- SwissProt: P82349 Mouse
- Unigene: 438953 Human
- Unigene: 89310 Mouse
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Alternative names
- 43 kDa dystrophin associated glycoprotein antibody
- 43 kDa dystrophin-associated glycoprotein antibody
- 43DAG antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-beta Sarcoglycan antibody (ab203392)
Immunohistochemical analysis of formalin-fixed, paraffin embedded rat pancreas tissue labeling beta Sarcoglycan with ab203392 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-beta Sarcoglycan antibody (ab203392)Immunohistochemical analysis of formalin-fixed, paraffin embedded mouse stomach tissue labeling beta Sarcoglycan with ab203392 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.
Datasheets and documents
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Datasheet download
References (0)
ab203392 has not yet been referenced specifically in any publications.
