Overview

  • Product name

    beta-Sitostanol, Cholesterol derivative
  • Description

    Cholesterol derivative
  • Biological description

    Cholesterol (ab142501) derivative. Reduces serum LDL-cholesterol. Shows antihypercholesterolemic effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    83-45-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (3S,8R,9S,10S,13R,14S,17R)-17-[(2R,5R)-5-Ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

  • Molecular weight

    416.72
  • Molecular formula

    C29H52O
  • PubChem identifier

    15559396
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC[C@H](CC[C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CC[C@@H](C4)O)C)C)C(C)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Chung RW  et al. Dietary sphingomyelin lowers hepatic lipid levels and inhibits intestinal cholesterol absorption in high-fat-fed mice. PLoS One 8:e55949 (2013). Read more (PubMed: 23409094) »
  • Ikeda I  et al. Antihypercholesterolemic activity of beta-sitostanol in rabbits. J Nutr Sci Vitaminol (Tokyo) 27:243-51 (1981). Read more (PubMed: 7288516) »
  • Sugano M  et al. A comparison of hypocholesterolemic activity of beta-sitosterol and beta-sitostanol in rats. J Nutr 107:2011-9 (1977). Read more (PubMed: 908959) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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