Overview

  • Product name

    beta-Sitosterol, Antitumor agent
  • Description

    Plant sterol. Various pharmacological effects. Antitumor agent
  • Purity

    > 97%
  • CAS Number

    83-46-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
  • Molecular weight

    414.71
  • Molecular formula

    C29H50O
  • PubChem identifier

    222284
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Sook SH  et al. Reactive Oxygen Species-Mediated Activation of AMP-Activated Protein Kinase and c-Jun N-terminal Kinase Plays a Critical Role in Beta-Sitosterol-Induced Apoptosis in Multiple Myeloma U266 cells. Phytother Res : (2013). Read more (PubMed: 23640957) »
  • Baskar AA  et al. ß-sitosterol prevents lipid peroxidation and improves antioxidant status and histoarchitecture in rats with 1,2-dimethylhydrazine-induced colon cancer. J Med Food 15:335-43 (2012). Read more (PubMed: 22353013) »
  • Moon DO  et al. beta-Sitosterol induces G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. Cancer Lett 264:181-91 (2008). Read more (PubMed: 18314257) »

Customer reviews and Q&As

Question
Answer

J’ai contacté le laboratoire qui m’a confirmé que ce produit devrait être reconstitué dans du DMSO.

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