Overview

  • Product name

    Bezafibrate, Pan-PPAR agonist
  • Description

    Pan-PPAR agonist
  • Biological description

    Pan-PPAR agonist (EC50 values are 50, 60 and 20 μM at PPARα, PPARγ and PPARδ human receptors respectively). More efficient than fenofibrate (ab120832) in reducing body weight and blood glucose. Antidiabetic and antihyperlipidemic effects.
  • Purity

    > 99%
  • CAS Number

    41859-67-0
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Inaba T  et al. Cholesterol reduction and atherosclerosis inhibition by bezafibrate in low-density lipoprotein receptor knockout mice. Hypertens Res 31:999-1005 (2008). Read more (PubMed: 18712055) »
  • Tenenbaum A  et al. Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons. Cardiovasc Diabetol 4:14 (2005). Read more (PubMed: 16168052) »
  • Willson TM  et al. The PPARs: from orphan receptors to drug discovery. J Med Chem 43:527-50 (2000). Read more (PubMed: 10691680) »

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