Overview

  • Product name
  • Description
    Goat polyclonal to BGT-1
  • Host species
    Goat
  • Specificity
    Reported variants represent identical protein: NP_001193860.1, NP_003035.3, NP_001116319.1, NP_001116320.1.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human BGT-1 aa 587-601 (C terminal).
    Sequence:

    CLDGSAGRNFGPSPT


    Database link: NP_003035.3

  • Positive control
    • Human Brain lysates from several regions including Olfactory bulb lysate.
  • General notes

    Previously labelled as SLC6A12.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab166933 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab166933 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 69 kDa.

Target

  • Function
    Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
  • Tissue specificity
    Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain.
  • Sequence similarities
    Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Betaine/GABA transporter 1 antibody
    • BGT-1 antibody
    • BGT1 antibody
    • Gamma aminobutyric acid transporter antibody
    • GAT2 antibody
    • Na(+)/Cl(-) betaine/GABA transporter antibody
    • S6A12_HUMAN antibody
    • Slc6a12 antibody
    • Sodium- and chloride-dependent betaine transporter antibody
    • Solute carrier family 6 (neurotransmitter transporter), member 12 antibody
    • Solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 antibody
    • Solute carrier family 6 member 12 antibody
    see all

Images

  • Anti-BGT-1 antibody (ab166933) at 1 µg/ml + Human Olfactory bulb lysate at 35 µg

    Developed using the ECL technique.

    Predicted band size: 69 kDa
    Additional bands at: 27 kDa. We are unsure as to the identity of these extra bands.



    Primary incubation was 1 hour.

    An additional band of unknown identity was also consistently observed at 27kDa. This band was successfully blocked by incubation with the immunizing peptide.

References

ab166933 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab166933.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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