Overview

  • Product name

  • Description

    Rabbit polyclonal to BGT-1
  • Host species

    Rabbit
  • Specificity

    This antibody detects endogenous levels of BGT-1 protein.
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human BGT-1 aa 548-593. The exact sequence is proprietary.
    Sequence:

    VCV PLFVVITLLK TRGPFRKRLR QLITPDSSLP QPKQHPCLDG SAG


    Database link: P48065

  • Positive control

    • HEK293T, sp2/0 and PC12 whole cell lysate
  • General notes

    Previously labelled as SLC6A12.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.20
    Preservative: 0.097% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    Purity is > 95% (by SDS-PAGE).
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab200676 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Predicted molecular weight: 69 kDa.

Target

  • Function

    Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
  • Tissue specificity

    Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain.
  • Sequence similarities

    Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Betaine/GABA transporter 1 antibody
    • BGT-1 antibody
    • BGT1 antibody
    • Gamma aminobutyric acid transporter antibody
    • GAT2 antibody
    • Na(+)/Cl(-) betaine/GABA transporter antibody
    • S6A12_HUMAN antibody
    • Slc6a12 antibody
    • Sodium- and chloride-dependent betaine transporter antibody
    • Solute carrier family 6 (neurotransmitter transporter), member 12 antibody
    • Solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 antibody
    • Solute carrier family 6 member 12 antibody
    see all

Images

  • All lanes : Anti-BGT-1 antibody (ab200676)

    Lane 1 : HEK293T whole cell lysate
    Lane 2 : sp2/0 whole cell lysate
    Lane 3 : PC12 whole cell lysate

    Predicted band size: 69 kDa

References

This product has been referenced in:

See 1 Publication for this product

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