Overview

  • Product name

  • Description

    Goat polyclonal to BHLHB5
  • Host species

    Goat
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human BHLHB5 aa 128-141 (Cysteine residue).
    Sequence:

    C-KYGESASRGSVAES


    Database link: Q8NFJ8

  • Positive control

    • WB: Human cerebellum lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab223261 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).

Target

  • Function

    Inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA.
  • Tissue specificity

    Brain-specific, with the highest expression in the cerebellum.
  • Sequence similarities

    Contains 1 basic helix-loop-helix (bHLH) domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Basic helix loop helix domain containing class B 5 1 2 5 antibody
    • Basic helix loop helix protein 5 antibody
    • Beta3 antibody
    • Beta3a antibody
    • BHE22_HUMAN antibody
    • bHLHB5 antibody
    • bHLHe22 antibody
    • CAGL85 antibody
    • Class B basic helix-loop-helix protein 5 antibody
    • Class E basic helix-loop-helix protein 22 antibody
    • Class II bHLH protein BHLHB5 antibody
    • TNRC20 antibody
    • Trinucleotide repeat containing 20 antibody
    • Trinucleotide repeat-containing gene 20 protein antibody
    see all

Images

  • Anti-BHLHB5 antibody (ab223261) at 1 µg/ml + Human cerebellum lysate at 35 µg

    Predicted band size: 37 kDa
    Observed band size: 37 kDa



    Primary incubation: 1 hour

References

ab223261 has not yet been referenced specifically in any publications.

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