Key features and details
- Rabbit polyclonal to BIGM103/ZIP8
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-BIGM103/ZIP8 antibody
DescriptionRabbit polyclonal to BIGM103/ZIP8
SpecificityPredicted not to cross-react with other ZIP family members.
Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human BIGM103/ZIP8 (C terminal).
- Human spleen tissue lysate
This product was previously labelled as BIGM103
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
Our Abpromise guarantee covers the use of ab106576 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 50 kDa.|
|IHC-P||Use at an assay dependent concentration.|
RelevanceBIGM103 belongs to a subfamily of proteins that show structural characteristics to zinc transporters. Zinc is an essential element. It acts as a cofactor for hundreds of enzymes and is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation.
Cellular localizationMembrane; Multi-pass membrane protein
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Immunofluorescence of BIGM103/ZIP8 in Human spleen tissue with ab106576 at 20 ug/mL.
Immunohistochemistry of BIGM103/ZIP8 in Human spleen tissue with ab106576 at 5 μg/mL.
Lane 1 : Anti-BIGM103/ZIP8 antibody (ab106576) at 1 µg/ml
Lane 2 : Anti-BIGM103/ZIP8 antibody (ab106576) at 2 µg/ml
All lanes : Human spleen tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 50 kDa
ab106576 has been referenced in 1 publication.
- Mei Z et al. Knockdown of zinc transporter ZIP8 expression inhibits neuroblastoma progression and metastasis in vitro. Mol Med Rep 18:477-485 (2018). PubMed: 29749445