Overview

  • Product name

    Bilobalide, GABA, glycine and 5-HT3 receptor antagonist
  • Description

    Non-competitive GABA, glycine and 5-HT3 receptor antagonist
  • Biological description

    Extract of Ginkgo biloba. Non-competitive GABAA and 5-HT3 receptor antagonist. Shows neuroprotective effects. Blood-brain-barrier permeable. Active in vivo.
  • Purity

    > 95%
  • CAS Number

    33570-04-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Lang D  et al. Neuroprotective effects of bilobalide are accompanied by a reduction of ischemia-induced glutamate release in vivo. Brain Res 1425:155-63 (2011). Read more (PubMed: 22032877) »
  • Kiewert C  et al. Role of GABAergic antagonism in the neuroprotective effects of bilobalide. Brain Res 1128:70-8 (2007). Read more (PubMed: 17134681) »
  • Thompson AJ  et al. Ginkgolide B and bilobalide block the pore of the 5-HT3receptor at a location that overlaps the picrotoxin binding site. Neuropharmacology 60:488-95 (0). Read more (PubMed: 21059362) »

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