Overview

  • Product name

    BIM 23056, Somatostatin receptor 5 (sst5) antagonist
  • Description

    Potent, selective somatostatin receptor 5 (sst5) antagonist
  • Biological description

    Potent, selective somatostatin receptor 5 (sst5) antagonist (Ki values are 5.7 (sst5), 10.8 (sst3), 16.6 (sst4), 142 (sst1) and >1000 nM (sst2) for human cloned receptors).
  • CAS Number

    150155-61-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Colucci R  et al. Somatostatin inhibits colon cancer cell growth through cyclooxygenase-2 downregulation. Br J Pharmacol 155:198-209 (2008). Read more (PubMed: 18587421) »
  • Wilkinson GF  et al. Potent antagonism by BIM-23056 at the human recombinant somatostatin sst5 receptor. Br J Pharmacol 118:445-7 (1996). Read more (PubMed: 8762063) »
  • Hoyer D  et al. Molecular pharmacology of somatostatin receptors. Naunyn Schmiedebergs Arch Pharmacol 350:441-53 (1994). Read more (PubMed: 7870182) »
  • Patel YC & Srikant CB Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5). Endocrinology 135:2814-7 (1994). Read more (PubMed: 7988476) »

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