Biopterin, coenzyme and cofactor of iNOS activity (ab142835)

Overview

  • Product name

    Biopterin, coenzyme and cofactor of iNOS activity
  • Description

    Coenzyme and obligate cofactor of iNOS activity
  • Biological description

    Coenzyme and obligate cofactor of iNOS activity. Regulated by adrenergic cyclic adenosine monophasphate-dependent mechanism. Cofactor for neurotransmitters. Active in vitro and in vivo.
  • Purity

    > 98%
  • CAS Number

    22150-76-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-Amino-6-[(1S,2R)-1,2-dihydroxypropyl]-1H-pteridin-4-one

  • Molecular weight

    237.22
  • Molecular formula

    C9H11N5O3
  • PubChem identifier

    444475
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO, DMF and 1M NaOH

     

  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C(C1=CN=C2C(=N1)C(=O)N=C(N2)N)O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Weinberg JB  et al. Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages. Blood 86:1184-95 (1995). Read more (PubMed: 7542498) »
  • Kammüller ME  et al. Urinary biopterin levels in mice during graft-versus-host reactions and during exposure to 5,5-diphenylhydantoin. Int J Immunopharmacol 13:463-73 (1991). Read more (PubMed: 1783459) »
  • Kapatos G  et al. Biosynthesis of biopterin: adrenergic cyclic adenosine monophosphate-dependent inhibition in the pineal gland. Science 213:1129-31 (1981). Read more (PubMed: 6168019) »

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