Biotin Anti-Acetylcholinesterase antibody (ab34533)
Key features and details
- Biotin Goat polyclonal to Acetylcholinesterase
- Reacts with: Cow
- Conjugation: Biotin
- Isotype: IgG
Overview
-
Product name
Biotin Anti-Acetylcholinesterase antibody
See all Acetylcholinesterase primary antibodies -
Description
Biotin Goat polyclonal to Acetylcholinesterase -
Host species
Goat -
Conjugation
Biotin -
Species reactivity
Reacts with: Cow -
Immunogen
Acetylcholinesterase from Bovine Erythrocytes.
-
General notes
10-20 Biotin molecules per goat IgG molecule.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 0.42% Potassium phosphate, 0.87% Sodium chloride, 1% BSA
BSA is IgG and Protease free -
Concentration information loading... -
Purity
IgG fraction -
Purification notes
This product is purified by a multi-step process including delipidation, salt fractionation, ion exchange chromatography and extensive dialysis against buffer. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Isotype control
-
Recombinant Protein
Applications
ELISA: 1/1000 - 1/2000.
This product has been assayed against 1.0µg of Acetylcholinesterase in a standard capture ELISA using Peroxidase conjugated streptavidin and ABTS (2,2'-azino-bis-[3-ethylbenthiazoline-6-sulfonic-acid]) as a substrate for 30 minutes at RT.
IM: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 68 kDa.
Suitable for other antibody based assays using streptavidin or avidin comjugates.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
-
Function
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis. -
Tissue specificity
Isoform H is highly expressed in erythrocytes. -
Sequence similarities
Belongs to the type-B carboxylesterase/lipase family. -
Cellular localization
Cell membrane; Cell junction > synapse. Secreted. Cell membrane and Nucleus. Only observed in apoptotic nuclei. - Information by UniProt
-
Database links
- Entrez Gene: 540446 Cow
- SwissProt: P23795 Cow
-
Alternative names
- ACEE antibody
- ACES_HUMAN antibody
- Acetylcholinesterase antibody
see all
Datasheets and documents
References (1)
ab34533 has been referenced in 1 publication.
- Freitas Leal JK et al. Acetylcholinesterase provides new insights into red blood cell ageing in vivo and in vitro. Blood Transfus 15:232-238 (2017). PubMed: 28518050
