Biotin Anti-Albumin antibody (ab174658)

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Key features and details

  • Biotin Goat polyclonal to Albumin
  • Conjugation: Biotin
  • Isotype: IgG

Overview

  • Product name

    Biotin Anti-Albumin antibody
    See all Albumin primary antibodies

  • Description

    Biotin Goat polyclonal to Albumin

  • Host species

    Goat

  • Conjugation

    Biotin

  • Species reactivity


    Predicted to work with: MouseDoes not react with: Cow, Human, Pig

  • Immunogen

    The details of the immunogen for this antibody are not available.

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

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Properties

Associated products

Target

  • Function

    Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

  • Tissue specificity

    Plasma.

  • Involvement in disease

    Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.

  • Sequence similarities

    Belongs to the ALB/AFP/VDB family.
    Contains 3 albumin domains.

  • Post-translational
    modifications

    Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
    Glycated in diabetic patients.
    Phosphorylation sites are present in the extracelllular medium.
    Acetylated on Lys-223 by acetylsalicylic acid.

  • Cellular localization

    Secreted.
  • Information by UniProt

  • Database links

    • Form

      There are 2 isoforms produced by alternative splicing.

    • Alternative names

      • alb antibody
      • ALBU_HUMAN antibody
      • Albumin (32 AA) antibody
      • Albumin (AA 34) antibody
      • cell growth inhibiting protein 42 antibody
      • DKFZp779N1935 antibody
      • GIG20 antibody
      • GIG42 antibody
      • Growth inhibiting protein 20 antibody
      • growth-inhibiting protein 20 antibody
      • OTTHUMP00000220436 antibody
      • OTTHUMP00000220438 antibody
      • OTTHUMP00000220439 antibody
      • PRO0883 antibody
      • PRO0903 antibody
      • PRO1341 antibody
      • PRO1708 antibody
      • PRO2044 antibody
      • PRO2619 antibody
      • PRO2675 antibody
      • Serum albumin antibody
      • UNQ696/PRO1341 antibody
      see all

    References (0)

    Publishing research using ab174658? Please let us know so that we can cite the reference in this datasheet.

    ab174658 has not yet been referenced specifically in any publications.

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