Key features and details
- Biotin Armenian hamster monoclonal [N418] to CD11c
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG
Product nameBiotin Anti-CD11c antibody [N418]
See all CD11c primary antibodies
DescriptionBiotin Armenian hamster monoclonal [N418] to CD11c
Host speciesArmenian hamster
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Mouse
Mouse spleen dendritic cells.
- Flow Cyt: C57BL/6 splenocytes.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark.
Storage bufferpH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.88% Sodium chloride, 0.1% Gelatin, 0.12% Monobasic dihydrogen sodium phosphate
Concentration information loading...
- PerCP/Cy5.5® Anti-CD11c antibody [N418] (ab111469)
- Anti-CD11c antibody [N418] - Low endotoxin, Azide free (ab185783)
- APC Anti-CD11c antibody [N418] (ab210306)
- APC/Cy7® Anti-CD11c antibody [N418] (ab210307)
- FITC Anti-CD11c antibody [N418] (ab210308)
- PE Anti-CD11c antibody [N418] (ab210309)
- PE/Cy7® Anti-CD11c antibody [N418] (ab210310)
- Alexa Fluor® 647 Anti-CD11c antibody [N418] (ab233046)
- Anti-CD11c antibody [N418] - BSA and Azide free (ab233173)
- violetFluor™ 450 Anti-CD11c antibody [N418] (ab242269)
- Anti-CD11c antibody [N418] (ab33483)
- Alexa Fluor® 488 Anti-CD11c antibody [N418] (ab33503)
Our Abpromise guarantee covers the use of ab95765 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use 0.25-0.5µg for 105-8 cells. Final volume of 100 µl.|
FunctionIntegrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Tissue specificityPredominantly expressed in monocytes and granulocytes.
Sequence similaritiesBelongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain.
DomainThe integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
- Information by UniProt
- 95 alpha chain antibody
- 95 antibody
- CD 11c antibody
ab95765 has been referenced in 8 publications.
- Xin KQ et al. Induction of robust immune responses against human immunodeficiency virus is supported by the inherent tropism of adeno-associated virus type 5 for dendritic cells. J Virol 80:11899-910 (2006). PubMed: 17005662
- Ohteki T et al. Essential roles of DC-derived IL-15 as a mediator of inflammatory responses in vivo. J Exp Med 203:2329-38 (2006). PubMed: 16966429
- Zhang J et al. The existence of CD11c+ sentinel and F4/80+ interstitial dendritic cells in dental pulp and their dynamics and functional properties. Int Immunol 18:1375-84 (2006). PubMed: 16849394
- Guiducci C et al. Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection. Cancer Res 65:3437-46 (2005). PubMed: 15833879
- Esche C et al. CD154 inhibits tumor-induced apoptosis in dendritic cells and tumor growth. Eur J Immunol 29:2148-55 (1999). PubMed: 10427977
- Metlay JP et al. The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies. J Exp Med 171:1753-71 (1990). PubMed: 2185332
- Bedford PG & Longstaffe JA Corneal pannus (chronic superficial keratitis) in the German shepherd dog. J Small Anim Pract 20:41-56 (1979). PubMed: 759720
- Cole DF Secretion of the aqueous humour. Exp Eye Res 25 Suppl:161-76 (1977). PubMed: 145370