Biotin Anti-CD69 antibody [H1.2F3] (ab25008)
Key features and details
- Biotin Armenian hamster monoclonal [H1.2F3] to CD69
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG
Overview
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Product name
Biotin Anti-CD69 antibody [H1.2F3]
See all CD69 primary antibodies -
Description
Biotin Armenian hamster monoclonal [H1.2F3] to CD69 -
Host species
Armenian hamster -
Conjugation
Biotin -
Species reactivity
Reacts with: Mouse -
Immunogen
Y245 dendritic epidermal T cell line (Mouse)
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General notes
ab25008 augments PMA-induced T-cell proliferation and induces redirected lysis of Fc receptor-bearing target cells by NK cells.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Affinity purified -
Primary antibody notes
ab25008 augments PMA-induced T-cell proliferation and induces redirected lysis of Fc receptor-bearing target cells by NK cells. -
Clonality
Monoclonal -
Clone number
H1.2F3 -
Isotype
IgG -
Light chain type
lambda -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Target
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Function
Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. -
Tissue specificity
Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets. -
Sequence similarities
Contains 1 C-type lectin domain. -
Developmental stage
Earliest inducible cell surface glycoprotein acquired during lymphoid activation. -
Post-translational
modificationsConstitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 12515 Mouse
- SwissProt: P37217 Mouse
- Unigene: 74745 Mouse
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Alternative names
- Activation inducer molecule (AIM/CD69) antibody
- Activation inducer molecule antibody
- AIM antibody
see all
Protocols
References (2)
ab25008 has been referenced in 2 publications.
- Yokoyama WM et al. Very early (VEA) and very late (VLA) activation antigens have distinct functions in T lymphocyte activation. Immunol Rev 109:153-76 (1989). PubMed: 2670747
- Yokoyama WM et al. Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation. J Immunol 141:369-76 (1988). PubMed: 2838547
