Biotin Anti-CD81 antibody [M38] (ab239238)

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Flow Cytometry - Biotin Anti-CD81 antibody [M38] (ab239238)

    Key features and details

    • Biotin Mouse monoclonal [M38] to CD81
    • Suitable for: Flow Cyt
    • Reacts with: Human
    • Conjugation: Biotin
    • Isotype: IgG1

    Conjugates logo Related conjugates and formulations

    APC APC/Cy7® FITC Unconjugated

    Overview

    • Product name

      Biotin Anti-CD81 antibody [M38]
      See all CD81 primary antibodies

    • Description

      Biotin Mouse monoclonal [M38] to CD81

    • Host species

      Mouse

    • Conjugation

      Biotin

    • Tested applications

      Suitable for: Flow Cytmore details

    • Species reactivity

      Reacts with: Human

    • Immunogen

      Tissue, cells or virus corresponding to Human CD81. MOLT-4 (human T-ALL cell line).

    • Positive control

      • Flow cyt: Human peripharal blood cells.

    • General notes

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    Properties

    • Form

      Liquid

    • Storage instructions

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. Store In the Dark.

    • Storage buffer

      pH: 7.40
      Preservative: 0.0975% Sodium azide
      Constituent: PBS
    • Concentration information loading...

    • Purity

      Size exclusion

    • Purification notes

      The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

    • Clonality

      Monoclonal

    • Clone number

      M38

    • Isotype

      IgG1

    • Research areas

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab239238 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Flow Cyt
    Use a concentration of 2 µg/ml.

    Designed for indirect immunofluorescence analysis by Flow Cytometry.
    Notes
    Flow Cyt
    Use a concentration of 2 µg/ml.

    Designed for indirect immunofluorescence analysis by Flow Cytometry.

    Target

    • Function

      May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May acts a the viral receptor for HCV.

    • Tissue specificity

      Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines.

    • Involvement in disease

      Defects in CD81 are the cause of immunodeficiency common variable type 6 (CVID6) [MIM:613496]; also called antibody deficiency due to CD81 defect. CVID6 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.

    • Sequence similarities

      Belongs to the tetraspanin (TM4SF) family.

    • Post-translational
      modifications

      Not glycosylated.

    • Cellular localization

      Membrane.
    • Information by UniProt

    • Database links

      • Alternative names

        • 26 kDa cell surface protein TAPA 1 antibody
        • 26 kDa cell surface protein TAPA-1 antibody
        • 26 kDa cell surface protein TAPA1 antibody
        • CD 81 antibody
        • CD81 antibody
        • CD81 antigen (target of antiproliferative antibody 1) antibody
        • CD81 antigen antibody
        • CD81 molecule antibody
        • CD81_HUMAN antibody
        • CVID6 antibody
        • S5.7 antibody
        • TAPA 1 antibody
        • TAPA1 antibody
        • Target of the antiproliferative antibody 1 antibody
        • Tetraspanin 28 antibody
        • Tetraspanin-28 antibody
        • Tetraspanin28 antibody
        • Tspan 28 antibody
        • Tspan-28 antibody
        • Tspan28 antibody
        see all

      Images

      • Flow Cytometry - Biotin Anti-CD81 antibody [M38] (ab239238)
        Flow Cytometry - Biotin Anti-CD81 antibody [M38] (ab239238)

        Surface staining of CD81 in human peripheral blood with ab239238, streptavidin-APC.

      Protocols

      To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

      Click here to view the general protocols

      References (0)

      Publishing research using ab239238? Please let us know so that we can cite the reference in this datasheet.

      ab239238 has not yet been referenced specifically in any publications.

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