Biotin Anti-Ferritin antibody (ab7333)
Key features and details
- Biotin Rabbit polyclonal to Ferritin
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG
Overview
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Product name
Biotin Anti-Ferritin antibody
See all Ferritin primary antibodies -
Description
Biotin Rabbit polyclonal to Ferritin -
Host species
Rabbit -
Conjugation
Biotin -
Species reactivity
Reacts with: Human -
Immunogen
Full length native protein (purified) corresponding to Human Ferritin. From human spleen
Database link: P02794 -
General notes
Biotinamidocaproate N-Hydroxysuccinimide Ester (BAC) Biotin/Protein Ratio: 10-20 BAC molecules per rabbit IgG molecule.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 0.88% Sodium chloride, 1% BSA, 0.42% Potassium phosphate -
Concentration information loading... -
Purity
IgG fraction -
Purification notes
This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Isotype control
Target
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Function
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. -
Sequence similarities
Belongs to the ferritin family.
Contains 1 ferritin-like diiron domain. - Information by UniProt
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Database links
- Entrez Gene: 2495 Human
- Entrez Gene: 2512 Human
- Omim: 608847 Human
- SwissProt: P02792 Human
- SwissProt: P02794 Human
- Unigene: 524910 Human
- Unigene: 645560 Human
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Form
Subunit structure: Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. In the human liver, the heavy chain is predominant. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited. -
Alternative names
- Cell proliferation-inducing gene 15 protein antibody
- Ferritin H subunit antibody
- Ferritin heavy chain antibody
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Protocols
Datasheets and documents
References (1)
ab7333 has been referenced in 1 publication.
- Bleicher AV et al. A sandwich enzyme-linked immunosorbent assay for the quantitation of human plasma ferritin. MethodsX 5:648-651 (2018). PubMed: 29998067
