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    biotin-fgf10-antibody-ab83439.pdf

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Cardiovascular Angiogenesis Growth Factors FGF FGF
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Biotin Anti-FGF10 antibody (ab83439)

  • Datasheet
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Key features and details

  • Biotin Goat polyclonal to FGF10
  • Reacts with: Human
  • Conjugation: Biotin
  • Isotype: IgG

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Conjugation
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Biotinylation Kit / Biotin Conjugation Kit (Fast, Type A) - Lightning-Link® (ab201795)
Primary
Product image
Anti-FGF10 antibody (ab71794)

View more associated products

Overview

  • Product name

    Biotin Anti-FGF10 antibody
    See all FGF10 primary antibodies
  • Description

    Biotin Goat polyclonal to FGF10
  • Host species

    Goat
  • Conjugation

    Biotin
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Highly pure (>98%) recombinant hFGF-10 (human Fibroblast Growth Factor-10).

  • Positive control

    • hFGF-10
  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Lyophilized:Reconstitute in sterile PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Constituent: PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Cardiovascular
    • Angiogenesis
    • Growth Factors
    • FGF
    • FGF
    • Signal Transduction
    • Growth Factors/Hormones
    • FGF
    • Stem Cells
    • Embryonic Stem Cells
    • Secreted
    • Cancer
    • Growth factors
    • FGF

Associated products

  • Isotype control

    • Biotin Goat IgG - Isotype Control (ab37376)

Target

  • Function

    Could be a growth factor active in the process of wound healing. Acts as a mitogen in the lung. May act in a manner similar to FGF-7.
  • Involvement in disease

    Defects in FGF10 are the cause of autosomal dominant aplasia of lacrimal and salivary glands (ALSG) [MIM:180920]. ALSG has variable expressivity, and affected individuals may have aplasia or hypoplasia of the lacrimal, parotid, submandibular and sublingual glands and absence of the lacrimal puncta. The disorder is characterized by irritable eyes, recurrent eye infections, epiphora (constant tearing) and xerostomia (dryness of the mouth), which increases the risk of dental erosion, dental caries, periodontal disease and oral infections.
    Defects in FGF10 are a cause of lacrimo-auriculo-dento-digital syndrome (LADDS) [MIM:149730]; also known as Levy-Hollister syndrome. LADDS is a form of ectodermal dysplasia, a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. LADDS is an autosomal dominant syndrome characterized by aplastic/hypoplastic lacrimal and salivary glands and ducts, cup-shaped ears, hearing loss, hypodontia and enamel hypoplasia, and distal limb segments anomalies. In addition to these cardinal features, facial dysmorphism, malformations of the kidney and respiratory system and abnormal genitalia have been reported. Craniosynostosis and severe syndactyly are not observed.
  • Sequence similarities

    Belongs to the heparin-binding growth factors family.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession O15520 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 2255 Human
    • Omim: 602115 Human
    • SwissProt: O15520 Human
    • Unigene: 664499 Human
    • Alternative names

      • BB213776 antibody
      • fd11d03 antibody
      • FGF 10 antibody
      • FGF-10 antibody
      • FGF10 antibody
      • FGF10_HUMAN antibody
      • Fibroblast growth factor 10 antibody
      • Keratinocyte growth factor 2 antibody
      • KGF 2 antibody
      • Produced by fibroblasts of urinary bladder lamina propria antibody
      • wu:fd11d03 antibody
      • zgc:109774 antibody
      see all

    Protocols

    • Western blot protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab83439? Please let us know so that we can cite the reference in this datasheet.

    ab83439 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    Question

    We are interested in quantifying FGF10 concentration using ELISA. We saw the result of ELISA on your home page (https://www.abcam.co.jp/FGF10-antibody-ab90207.html#FGF10-Primary-antibodies-ab90207-3.jpg). Will you please provide us the detailed protocol of this procedure?

    Read More

    Abcam community

    Verified customer

    Asked on May 08 2012

    Answer

    Thank you for your enquiry.

    The data on the datasheet is a sandwich ELISA result. This ab90207 FGF10 antibody can be paired with ab83439 FGF10 antibody (Biotin), where ab90207 is the capture antibody and ab83439 is the detection antibody.

    Recommended dilutions:
    1) ab90207 use at 5ug/ml
    2) ab83439 use at 0.25 - 1 µg/ml

    For more protocol details, please refer to our protocol links below.

    https://www.abcam.com/index.html?pageconfig=resource&rid=11422 (English)
    https://www.abcam.co.jp/index.html?pageconfig=resource&rid=11422 (Japanese)
    https://www.abcam.com/ps/pdf/protocols/Sandwich_Elisa_diagram.pdf (Diagram)

    I hope this information will be helpful. If there is anything else that I can help you with please do not hesitate to contact me.

    Have a nice day!

    Read More

    Abcam Scientific Support

    Answered on May 08 2012

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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