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    biotin-human-serum-albumin-antibody-ab40378.pdf

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Cardiovascular Blood Serum Proteins
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Biotin Anti-Human Serum Albumin antibody (ab40378)

  • Datasheet
  • SDS
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Key features and details

  • Biotin Goat polyclonal to Human Serum Albumin
  • Reacts with: Human
  • Conjugation: Biotin
  • Isotype: IgG

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Recombinant Human Serum Albumin protein (His tag) (ab217817)
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Overview

  • Product name

    Biotin Anti-Human Serum Albumin antibody
    See all Human Serum Albumin primary antibodies
  • Description

    Biotin Goat polyclonal to Human Serum Albumin
  • Host species

    Goat
  • Conjugation

    Biotin
  • Specificity

    Monospecificity of this antibody has been determined by ELISA against normal human albumin.
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length native protein (purified) (Human)

  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituents: 0.0268% PBS, 1% BSA
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Cardiovascular
    • Blood
    • Serum Proteins
    • Stem Cells
    • Lineage Markers
    • Endoderm
    • Cancer
    • Cancer Metabolism
    • Metabolic signaling pathway
    • Metabolism of lipids and lipoproteins
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipid metabolism
    • Metabolism
    • Types of disease
    • Cancer

Associated products

  • Isotype control

    • Biotin Goat IgG - Isotype Control (ab37376)
  • Recombinant Protein

    • Recombinant Human Serum Albumin protein (His tag) (ab217817)

Applications

  • Application notes
    ELISA: 1/20000. WB: Use at an assay dependent dilution. Predicted molecular weight: 69 kDa. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
    • Tissue specificity

      Plasma.
    • Involvement in disease

      Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
    • Sequence similarities

      Belongs to the ALB/AFP/VDB family.
      Contains 3 albumin domains.
    • Post-translational
      modifications

      Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
      Glycated in diabetic patients.
      Phosphorylation sites are present in the extracelllular medium.
      Acetylated on Lys-223 by acetylsalicylic acid.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P02768 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 213 Human
      • Omim: 103600 Human
      • SwissProt: P02768 Human
      • Unigene: 418167 Human
      • Alternative names

        • alb antibody
        • ALBU_HUMAN antibody
        • Albumin (32 AA) antibody
        • Albumin (AA 34) antibody
        • Albumin antibody
        • Analbuminemia antibody
        • Bisalbuminemia antibody
        • Cell growth inhibiting protein 42 antibody
        • DKFZp779N1935 antibody
        • Dysalbuminemic hyperthyroxinemia antibody
        • Growth inhibiting protein 20 antibody
        • HSA antibody
        • Hyperthyroxinemia dysalbuminemic antibody
        • PRO0883 antibody
        • PRO0903 antibody
        • PRO1341 antibody
        • Serum albumin antibody
        see all

      Protocols

      • Western blot protocols

      Click here to view the general protocols

      Datasheets and documents

      • Datasheet
      • SDS
    • References (0)

      Publishing research using ab40378? Please let us know so that we can cite the reference in this datasheet.

      ab40378 has not yet been referenced specifically in any publications.

      Customer reviews and Q&As

      Show All Reviews Q&A
      Submit a review Submit a question

      ELISA abreview for Anti-Human Serum Albumin antibody (Biotin)

      Excellent
      Abreviews
      Abreviews
      abreview image
      Application
      ELISA
      Sample
      Mouse Serum (ICR Mouse serum)
      Specification
      ICR Mouse serum
      Blocking step
      BSA as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 1% · Temperature: 25°C
      Type
      Sandwich (Detection)
      Read More

      Abcam user community

      Verified customer

      Submitted Dec 25 2019

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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