Key features and details
- Biotin Rat monoclonal [3C7] to IL-2 Receptor alpha
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG2b
Product nameBiotin Anti-IL-2 Receptor alpha antibody [3C7]
See all IL-2 Receptor alpha primary antibodies
DescriptionBiotin Rat monoclonal [3C7] to IL-2 Receptor alpha
Species reactivityReacts with: Mouse
The details of the immunogen for this antibody are not available.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.1% Sodium azide
Concentration information loading...
Light chain typekappa
IP: Use at an assay dependent dilution.
Inhibition of IL-2 or mitogen-induced T cell proliferation: Use at an assay dependent dilution.
In vitro blocking of IL-2 binding: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionReceptor for interleukin-2.
Involvement in diseaseGenetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
Sequence similaritiesContains 2 Sushi (CCP/SCR) domains.
- Information by UniProt
- Interleukin 2 receptor alpha chain antibody
- CD25 antibody
- CD25 antigen antibody
ab25297 has not yet been referenced specifically in any publications.