Biotin Anti-IL3RA/CD123 antibody [6H6] (ab21560)

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Key features and details

  • Biotin Mouse monoclonal [6H6] to IL3RA/CD123
  • Suitable for: Flow Cyt
  • Reacts with: Human
  • Conjugation: Biotin
  • Isotype: IgG1

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Alexa Fluor® 700 APC FITC PE PE/Cy5® PE/Cy7® PerCP/Cy5.5® Unconjugated

Overview

  • Product name

    Biotin Anti-IL3RA/CD123 antibody [6H6]
    See all IL3RA/CD123 primary antibodies

  • Description

    Biotin Mouse monoclonal [6H6] to IL3RA/CD123

  • Host species

    Mouse

  • Conjugation

    Biotin

  • Tested applications

    Suitable for: Flow Cytmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Tissue, cells or virus corresponding to Human IL3RA/CD123.
    Database link: P26951

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • Storage buffer

    pH: 7.20
    Preservative: 0.09% Sodium azide
    Constituent: PBS
  • Concentration information loading...

  • Purity

    Protein G purified

  • Clonality

    Monoclonal

  • Clone number

    6H6

  • Isotype

    IgG1

  • Light chain type

    kappa

  • Research areas

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab21560 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
Use at an assay dependent concentration.

Use 0.5ug for 10^6 cells in 100ul or 100ul whole blood. This antibody has been tested using immunofluorescent staining with flow cytometric analysis. ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
Notes
Flow Cyt
Use at an assay dependent concentration.

Use 0.5ug for 10^6 cells in 100ul or 100ul whole blood. This antibody has been tested using immunofluorescent staining with flow cytometric analysis. ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • Function

    This is a receptor for interleukin-3.

  • Sequence similarities

    Belongs to the type I cytokine receptor family. Type 5 subfamily.

  • Domain

    The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.

  • Cellular localization

    Membrane.
  • Information by UniProt

  • Database links

    • Alternative names

      • CD123 antibody
      • CD123 antigen antibody
      • hIL 3Ra antibody
      • hIL-3Ra antibody
      • hIL3Ra antibody
      • IL 3 receptor alpha SP2 isoform antibody
      • IL 3R alpha antibody
      • IL-3 receptor subunit alpha antibody
      • IL-3R subunit alpha antibody
      • IL-3R-alpha antibody
      • IL-3RA antibody
      • IL3 Receptor alpha antibody
      • IL3R antibody
      • Il3ra antibody
      • IL3RA_HUMAN antibody
      • IL3RAX antibody
      • IL3RAY antibody
      • IL3RX antibody
      • IL3RY antibody
      • Interleukin 3 receptor alpha chain antibody
      • Interleukin 3 receptor, alpha (low affinity) antibody
      • Interleukin 3 receptor, alpha antibody
      • Interleukin-3 Receptor alpha antibody
      • Interleukin-3 receptor subunit alpha antibody
      • Interleukin3 receptor antibody
      • Interleukin3 receptor, Y-chromosomal antibody
      see all

    References (2)

    Publishing research using ab21560? Please let us know so that we can cite the reference in this datasheet.

    ab21560 has been referenced in 2 publications.

    • Li H  et al. Physiological stress-induced corticosterone increases heme uptake via KLF4-HCP1 signaling pathway in hippocampus neurons. Sci Rep 7:5745 (2017). PubMed: 28720846
    • Sun Q  et al. Monoclonal antibody 7G3 recognizes the N-terminal domain of the human interleukin-3 (IL-3) receptor alpha-chain and functions as a specific IL-3 receptor antagonist. Blood 87:83-92 (1996). PubMed: 8547680

    Customer reviews and Q&As

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