Biotin Anti-IL3RA/CD123 antibody [6H6] (ab21560)
Key features and details
- Biotin Mouse monoclonal [6H6] to IL3RA/CD123
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG1
Overview
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Product name
Biotin Anti-IL3RA/CD123 antibody [6H6]
See all IL3RA/CD123 primary antibodies -
Description
Biotin Mouse monoclonal [6H6] to IL3RA/CD123 -
Host species
Mouse -
Conjugation
Biotin -
Species reactivity
Reacts with: Human -
Immunogen
Tissue, cells or virus corresponding to IL3RA/CD123.
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General notes
Previously labelled as IL3RA.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
6H6 -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
- PerCP/Cy5.5® Anti-IL3RA/CD123 antibody [6H6], prediluted (ab155368)
- PerCP/Cy5.5® Anti-IL3RA/CD123 antibody [6H6] (ab157332)
- Anti-IL3RA/CD123 antibody [6H6] (ab21562)
- PE/Cy5® Anti-IL3RA/CD123 antibody [6H6] (ab232697)
- PE/Cy7® Anti-IL3RA/CD123 antibody [6H6] (ab233585)
- APC Anti-IL3RA/CD123 antibody [6H6] (ab239280)
- PE Anti-IL3RA/CD123 antibody [6H6] (ab93523)
- APC Anti-IL3RA/CD123 antibody [6H6] (ab95781)
- FITC Anti-IL3RA/CD123 antibody [6H6] (ab95782)
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Isotype control
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Recombinant Protein
Target
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Function
This is a receptor for interleukin-3. -
Sequence similarities
Belongs to the type I cytokine receptor family. Type 5 subfamily. -
Domain
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 3563 Human
- Omim: 308385 Human
- Omim: 430000 Human
- SwissProt: P26951 Human
- Unigene: 632790 Human
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Alternative names
- CD123 antibody
- CD123 antigen antibody
- hIL 3Ra antibody
see all
Datasheets and documents
References (2)
ab21560 has been referenced in 2 publications.
- Li H et al. Physiological stress-induced corticosterone increases heme uptake via KLF4-HCP1 signaling pathway in hippocampus neurons. Sci Rep 7:5745 (2017). PubMed: 28720846
- Sun Q et al. Monoclonal antibody 7G3 recognizes the N-terminal domain of the human interleukin-3 (IL-3) receptor alpha-chain and functions as a specific IL-3 receptor antagonist. Blood 87:83-92 (1996). PubMed: 8547680
