Biotin-LC-NHS (Succinimidyl 6-(biotinamido)hexanoate), Amine-reactive biotinylation agent (ab145617)

Overview

  • Product name

    Biotin-LC-NHS (Succinimidyl 6-(biotinamido)hexanoate), Amine-reactive biotinylation agent
  • Description

    Amine-reactive, medium length biotinylation agent
  • Biological description

    Amine-reactive, medium length (22.4 angstroms) biotinylation agent. Forms irreversible amide links via an NHS ester group at the end of the spacer arm. Suitable for use under alkaline conditions (pH~8-9). Biotin-LC-LC-NHS (ab145618) also available.
  • Purity

    > 95%
  • CAS Number

    72040-63-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2,5-Dioxopyrrolidin-1-yl) 6-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]hexanoate
  • Molecular weight

    454.54
  • Molecular formula

    C20H30N4O6S
  • PubChem identifier

    83874
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1CC(=O)N(C1=O)OC(=O)CCCCCNC(=O)CCCC[C@H]2[C@@H]3[C@H](CS2)NC(=O)N3
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Frost SH  et al. In vitro evaluation of avidin antibody pretargeting using 211At-labeled and biotinylated poly-L-lysine as effector molecule. Cancer 116:1101-10 (2010). Read more (PubMed: 20127953) »
  • Kim H  et al. Characterization of mixed self-assembled monolayers for immobilization of streptavidin using chemical force microscopy. Ultramicroscopy 108:1140-3 (2008). Read more (PubMed: 18555612) »
  • Yin XB  et al. Microfluidic chip with electrochemiluminescence detection using 2-(2-aminoethyl)-1-methylpyrrolidine labeling. J Chromatogr A 1091:158-62 (2005). Read more (PubMed: 16395805) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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