Biotin Anti-Neurogranin antibody (ab240487)
Key features and details
- Biotin Goat polyclonal to Neurogranin
- Suitable for: WB
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG
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Overview
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Product name
Biotin Anti-Neurogranin antibody
See all Neurogranin primary antibodies -
Description
Biotin Goat polyclonal to Neurogranin -
Host species
Goat -
Conjugation
Biotin -
Specificity
Reported variants represent identical protein: NP_006167.1, NP_001119653.1 -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Goat, Cow
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Immunogen
Synthetic peptide corresponding to Human Neurogranin aa 45-55 (internal sequence) (Cysteine residue). NP_006167.1
Sequence:C-KIKSGERGRKG
Database link: Q92686 -
Positive control
- WB: Human brain (frontal cortex) lysate.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. Store In the Dark. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Isotype control
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab240487 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 8 kDa. 1 hour primary incubation is recommended for this product. |
Target
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Function
Acts as a "third messenger" substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium. -
Tissue specificity
In the cerebral cortex, found in the cell bodies of neurons in layers II-VI, and in apical and basal dendrites of pyramidal neurons. Is not found in the dendrites in patients with Alzheimer disease. -
Sequence similarities
Belongs to the neurogranin family.
Contains 1 collagen-like domain.
Contains 1 IQ domain. - Information by UniProt
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Database links
- Entrez Gene: 4900 Human
- Omim: 602350 Human
- SwissProt: P35722 Cow
- SwissProt: P54877 Goat
- SwissProt: Q92686 Human
- Unigene: 524116 Human
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Alternative names
- Protein kinase C substrate RC3 antibody
- Calmodulin binding protein antibody
- Hng antibody
see all
Images
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Western blot - Biotin Anti-Neurogranin antibody (ab240487)Biotin Anti-Neurogranin antibody (ab240487) at 0.1 µg/ml + Human brain (Frontal cortex) lysate in RIPA buffer at 35 µg
Predicted band size: 8 kDaPrimary incubation was 1 hour. Detected by chemiluminescence.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab240487 has not yet been referenced specifically in any publications.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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