Biotin Anti-PPAR alpha antibody (ab48369)

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Key features and details

  • Biotin Rabbit polyclonal to PPAR alpha
  • Suitable for: IP, WB
  • Reacts with: Human
  • Conjugation: Biotin
  • Isotype: IgG

Overview

  • Product name

    Biotin Anti-PPAR alpha antibody
    See all PPAR alpha primary antibodies

  • Description

    Biotin Rabbit polyclonal to PPAR alpha

  • Host species

    Rabbit

  • Conjugation

    Biotin

  • Tested applications

    Suitable for: IP, WBmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Recombinant Human PPAR alpha (expressed in E. coli).

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab48369 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP
Use at an assay dependent concentration.
WB
Use at an assay dependent concentration.
Notes
IP
Use at an assay dependent concentration.
WB
Use at an assay dependent concentration.

Target

  • Function

    Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.

  • Tissue specificity

    Skeletal muscle, liver, heart and kidney.

  • Sequence similarities

    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.

  • Cellular localization

    Nucleus.
  • Information by UniProt

  • Database links

    • Alternative names

      • hPPAR antibody
      • MGC2237 antibody
      • MGC2452 antibody
      • NR1C1 antibody
      • Nuclear receptor subfamily 1 group C member 1 antibody
      • OTTHUMP00000197740 antibody
      • OTTHUMP00000197741 antibody
      • Peroxisome proliferative activated receptor alpha antibody
      • Peroxisome proliferator activated receptor alpha antibody
      • Peroxisome proliferator-activated receptor alpha antibody
      • PPAR antibody
      • PPAR-alpha antibody
      • ppara antibody
      • PPARA_HUMAN antibody
      • PPARalpha antibody
      see all

    References (0)

    Publishing research using ab48369? Please let us know so that we can cite the reference in this datasheet.

    ab48369 has not yet been referenced specifically in any publications.

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