Biotin Anti-SCGF beta antibody (ab84442)

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Key features and details

  • Biotin Goat polyclonal to SCGF beta
  • Reacts with: Human
  • Conjugation: Biotin
  • Isotype: IgG

Overview

  • Product name

    Biotin Anti-SCGF beta antibody
    See all SCGF beta primary antibodies

  • Description

    Biotin Goat polyclonal to SCGF beta

  • Host species

    Goat

  • Conjugation

    Biotin

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Highly pure (>98%) recombinant full length Human protein

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.

    One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.

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Properties

  • Form

    Lyophilized:Centrifuge vial prior to opening. Reconstitute in 50ul sterile PBS containing 0.1% BSA

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • Storage buffer

    Constituents: 0.1% BSA, PBS
  • Concentration information loading...

  • Purity

    Immunogen affinity purified

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Target

  • Function

    Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.

  • Tissue specificity

    Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.

  • Sequence similarities

    Contains 1 C-type lectin domain.

  • Developmental stage

    In the bone marrow, expression is limited to immature neutrophils. Expression was not detected in circulating mature neutrophils.

  • Post-translational
    modifications

    O-glycosylated. Probably sulfated on the O-glycans.

  • Cellular localization

    Cytoplasm. Secreted.
  • Information by UniProt

  • Database links

    • Alternative names

      • C type lectin domain family 11 member A antibody
      • C type lectin superfamily member 3 antibody
      • C-type lectin domain family 11 member A antibody
      • C-type lectin superfamily member 3 antibody
      • CLC11_HUMAN antibody
      • CLEC11A antibody
      • CLECSF3 antibody
      • LSLCL antibody
      • Lymphocyte secreted C type lectin antibody
      • Lymphocyte secreted C-type lectin antibody
      • p47 antibody
      • Stem cell growth factor antibody
      see all

    References (0)

    Publishing research using ab84442? Please let us know so that we can cite the reference in this datasheet.

    ab84442 has not yet been referenced specifically in any publications.

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