Key features and details
- Biotin Armenian hamster monoclonal [UC7-13D5] to TCR gamma + TCR delta
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG
Product nameBiotin Anti-TCR gamma + TCR delta antibody [UC7-13D5]
See all TCR gamma + TCR delta primary antibodies
DescriptionBiotin Armenian hamster monoclonal [UC7-13D5] to TCR gamma + TCR delta
Host speciesArmenian hamster
Specificityab25209 is specific for the gamma-delta heterodimer and plate-bound ab25209 activates gamma-delta TCR bearing cells. This antibody does not react with alpha-beta TCR-expressing T cells.
Species reactivityReacts with: Mouse
The details of the immunogen for this antibody are not available.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.1% Sodium azide
Concentration information loading...
RelevanceT cell receptors (TCR) recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one a and one b chain or one d and one g chain. This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level. The g/d TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most g/d T cells are CD4-/CD8-, some are CD8+. T cells expressing the g/d TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease.
Cellular localizationType I membrane protein
- CD_antigen=CD3d antibody
- CD3D antibody
- CD3G antibody
ab25209 has been referenced in 1 publication.
- Dent AL et al. Self-reactive gamma delta T cells are eliminated in the thymus. Nature 343:714-9 (1990). PubMed: 1968227